Glossary / Lexicon

NSAID (Nonsteroidal anti-inflammatory drugs) is a class of medications used to treat pain, fever, and inflammation. NSAIDs work by blocking the production of certain chemicals in the body that cause pain and inflammation, such as prostaglandins.

NSAIDs are commonly used in the field of psychology to treat a variety of conditions that involve pain or inflammation, including chronic pain, arthritis, and migraine headaches. They are also sometimes used to manage symptoms of depression and anxiety, as some studies have suggested that inflammation may play a role in these conditions.

Some examples of NSAIDs include aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), and celecoxib (Celebrex). These medications are available over-the-counter or by prescription, depending on the specific drug and dose.

NSAIDs are generally considered safe and effective for short-term use in most people, but can cause side effects in some individuals. Common side effects include stomach upset, heartburn, and headache. More serious side effects can include bleeding in the stomach or intestines, high blood pressure, and kidney damage. Individuals with certain medical conditions, such as a history of stomach ulcers or heart disease, may be at increased risk for side effects from NSAIDs and should consult with their healthcare provider before taking these medications.

There are also other classes of medications that are similar to NSAIDs in their mechanism of action, but may have different side effect profiles or be used for different indications. These include:

1. Acetaminophen: This medication is used to treat pain and fever, but does not have anti-inflammatory effects like NSAIDs. Acetaminophen is generally considered safe and well-tolerated, but can cause liver damage if taken in excessive doses.

2. Corticosteroids: These medications are used to reduce inflammation in a wide range of conditions, including allergies, asthma, and autoimmune disorders. Corticosteroids are generally prescribed by a healthcare provider and can have many side effects, including weight gain, increased appetite, and increased risk of infections.

3. COX-2 inhibitors: These medications are a subclass of NSAIDs that selectively block the COX-2 enzyme, which is involved in pain and inflammation. COX-2 inhibitors may have a lower risk of stomach ulcers and bleeding compared to traditional NSAIDs, but may also increase the risk of heart attack and stroke.

In summary, NSAIDs are a class of medications commonly used in psychology to treat pain, fever, and inflammation. These medications work by blocking the production of certain chemicals in the body that cause pain and inflammation. While NSAIDs are generally considered safe and effective for short-term use, they can cause side effects in some individuals and should be used with caution in those with certain medical conditions. Other medications with similar mechanisms of action include acetaminophen, corticosteroids, and COX-2 inhibitors.