Catechol-o-methyltransferase (COMT) refers to enzyme that converts catecholamines into synaptically inactive forms.
Catechol-O-methyltransferase (COMT) is an enzyme that plays a role in the metabolism of neurotransmitters, such as dopamine, in the brain. COMT is involved in the breakdown of dopamine, and variations in the COMT gene can affect the activity of the enzyme and the level of dopamine in the brain.
In psychology, COMT has been studied in relation to a variety of mental health conditions and behaviors, such as:
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Schizophrenia: Some research suggests that variations in the COMT gene may be associated with an increased risk for schizophrenia, although the relationship is complex and not fully understood.
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Cognitive function: Some research suggests that COMT may be related to cognitive function, including working memory, attention, and decision-making.
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Substance abuse: Some research has explored the relationship between COMT and the risk for substance abuse, including the use of tobacco, alcohol, and other drugs.
It is important to note that COMT is just one of many factors that can influence mental health and behavior, and that the relationship between COMT and mental health is complex and not fully understood. Further research is needed to fully understand the role of COMT in psychology.