Catechol-o-methyltransferase (COMT) refers to enzyme that converts catecholamines into synaptically inactive forms.

Catechol-O-methyltransferase (COMT) is an enzyme that plays a role in the metabolism of neurotransmitters, such as dopamine, in the brain. COMT is involved in the breakdown of dopamine, and variations in the COMT gene can affect the activity of the enzyme and the level of dopamine in the brain.

In psychology, COMT has been studied in relation to a variety of mental health conditions and behaviors, such as:

It is important to note that COMT is just one of many factors that can influence mental health and behavior, and that the relationship between COMT and mental health is complex and not fully understood. Further research is needed to fully understand the role of COMT in psychology.