Glossary / Lexicon

Deutsch: Pick-Krankheit / Español: Enfermedad de Pick / Português: Doença de Pick / Français: Maladie de Pick / Italiano: Malattia di Pick

Pick’s disease refers to rare neurological disorder that results in Pre-senile Dementia.

Pick's disease is a relatively rare degenerative disease or neurological disorder that affects the frontal and temporal lobes of the cerebral cortex and that can cause Dementia or that results in Presenile Dementia. Moreover. Pick's disease is a form of Dementia characterized by a slowly progressive deterioration of social skills and changes in personality leading to impairment of intellect, memory, and language. (Please see also Dementia)

Other definition:

Pick's disease is a rare neurodegenerative disease that causes progressive destruction of nerve cells in the brain. Symptoms include loss of speech (aphasia) and dementia. While some of the symptoms can initially be alleviated, the disease progresses and patients often die within two to ten years. A defining characteristic of the disease is build-up of tau proteins in neurons, accumulating into silver-staining, spherical aggregations known as "Pick bodies".
While the term Pick's disease was once used to represent a class of clinical syndromes with symptoms attributable to frontal and temporal lobe dysfunction, it is now used among professionals to mean a specific pathology that is one of the causes of frontotemporal lobar degeneration. Some people use the term Pick's disease to mean the more general clinical syndrome of frontotemporal lobar degeneration, but this has previously led to confusion among professionals and patients and so its use should be restricted to the specific pathological subtype described below. It is also known as Pick disease and PiD (not to be confused with pelvic inflammatory disease (PID) or Parkinson's disease (PD)).