Glossary / Lexicon

Mast cell is defined as connective tissue cell that releases histamine and other chemicals in response to certain stimuli, as in injury.

Mast cells are a type of white blood cell that play an important role in the body's immune system. They are primarily found in tissues that are in contact with the external environment, such as the skin, respiratory tract, and digestive system.

Examples of mast cell functions include:

1. Allergic reactions: Mast cells are known for their role in allergic reactions. When an allergen enters the body, it can trigger mast cells to release histamine and other chemical mediators, leading to symptoms such as swelling, itching, and inflammation.

2. Immune response: Mast cells are also involved in the body's immune response to pathogens such as bacteria and viruses. They can release cytokines and other immune molecules that help to recruit other immune cells to the site of infection.

3. Wound healing: Mast cells are involved in the process of wound healing. They release factors that can promote the growth of blood vessels and the migration of cells involved in tissue repair.

4. Neurological function: Recent research has suggested that mast cells may also play a role in neurological function. Mast cells have been found in the brain and are thought to be involved in processes such as pain perception and stress response.

Dysfunction of mast cells has been implicated in a variety of conditions, including allergies, asthma, autoimmune disorders, and gastrointestinal diseases. Therefore, understanding the role of mast cells in the body's immune system can be important for developing treatments and therapies for these conditions.